Lehninger Principles of Biochemistry 6th edition is a book on biochemistry. David L. Nelson and Michael M. Cox co-are authors this book. They have their affiliation with University of Wisconsin Madison. Biochemistry is the branch of knowledge dealing with study of chemical processes that take place in living things. Similarly, living organisms have complex metabolic pathways on which crucial biochemical reactions take place. Every human activity circles around biochemical processes.
Review on Lehninger Principles of Biochemistry 6th edition
Biochemistry asks how properties of living organisms arise from bio-molecules, showing that these molecules act solely by physical and chemical laws of nature.
- Six distinguishing features of living organisms
- High degree of chemical complexity and microscopic organization
- Systems for extracting, transforming and using energy from the environment
- Defined function for an organism’s components and regulated interaction among them
- Mechanisms for sensing and responding to alterations in their surroundings
- Capacity for precise self replication and self assembly
- Capacity to change over time by gradual evolution
- Plasma membrance
- Nucleus/ Nucleoid
Three different domains of life:
Lehninger Principles of Biochemistry explains principles of Biochemistry. But the scope of book is much wider. This book is a detailed treatise and a comprehensive book. It encompasses all the topics ranging from simpler to complex ones. At the same time, the writing style of book is reader friendly but not too much simpler.
As a reader of Lehninger Principles of Biochemistry one would get familiar with 3 main areas. These are the three main divisions of the book. Every part contains multiple chapters. Starting from introduction of biochemistry book features part 1 named as “structure and catalysis”. This part contains introduction about basic bio-molecules found in living organisms. The structure, function and chemistry of these molecules is thoroughly discussed. These molecules range from water molecules to bio signaling molecules.
Then there are a bunch of chapters on metabolism and bioenergetics. It forms 2nd part of Lehninger Principles of Biochemistry. Metabolism of every bio-molecule is crucial for life. Bioenergetics means the energy changes that take place in living things. There are several important processes which the book separately discusses. Synthesis and formation of many important life substances is also a part of this division.
Information pathways is the 3rd and last part. It contains 5 chapters. It tackles the most complex biochemical processes occurring in nature. The transfer of information and heredity is through genes. Similarly, DNA, RNA and proteins also play an important part. The metabolism of these molecules forms information pathways. All these processes are interlinked and represent gene expression. Finally, Detailed information about information pathways is also present in the book. So, comprising of more than 1100 words Lehninger Principles of Biochemistry can be regarded as Encyclopedia of Biochemistry.
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